Postdoctoral Scientist - Bioinformatics and Functional Genomics - Knott Lab

For more information about Dr. Knott's Laboratory, follow this link:

https://www.cedars-sinai.edu/Research/Research-Labs/Knott-Lab/

The Knott Lab is searching for a computational biologist post-doctoral scientist that is interested in applying single cell profiling technologies to study breast cancer progression. We are part of the Center for Bioinformatics and Functional Genomics at Cedars Sinai Medical Institute, in Los Angeles California. The lab is currently focused on developing molecular and computational tools to study the mechanisms that cancer cells employ to metastasize and evade therapy. We are particularly interested in next-generation therapeutics that target the interactions between malignant and non-malignant tumor cell types, such as immune checkpoint inhibitors. 

The chosen candidate will work alongside oncologists and bench scientists to generate clinically actionable hypotheses from novel single cell datasets. These will include 10X genomics data from dissociated tumors as well as information from in situ experiments, where single cell expression profiles are extracted from intact tumor tissue. In addition, the selected applicant will be a key contributor to the design and data analysis portion of follow-up validation studies, which employ our novel genome-wide CRISPR reagents. This position offers a unique opportunity for a post doc with a computational specialty to fully immerse themselves in the discovery process.

This is a 2-year term position

Job Duties:

Education Required: 

Experience Required: 

Physical Demands:

Able to perform moderate lifting. Able to sit, stand, and walk for prolonged periods of time.  Able to operate standard office equipment. Able to exercise physical ability and perspective acuity to satisfactorily perform essential job functions.