Summer Intern, Drug Metabolism & Pharmacokinetics

Intern, Drug Metabolism & Pharmacokinetics

The Vertex Summer Internship Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our internship program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are fearless" is in everything we do. Students can expect to be challenged by their summer project plan, connect with other interns, and feel valued by the Vertex community. Not only will interns learn about their day-to-day tasks through their specific work assignments, but they will interact and have exposure to our organizational leaders and their teams through a series of Professional Development Workshops.

Be FEARLESS... Join us and help kick start the path to your career!

Job Description

Vertex Pharmaceuticals Inc. is seeking a highly motivated, creative and innovative undergraduate or graduate intern to join our in vivo non-GLP Bioanalysis (BA) group in the Department of Drug Metabolism & Pharmacokinetics (DMPK) at Boston site. Our BA group provides comprehensive quantification and analysis for small molecule drugs and/or metabolites and biomarkers from discovery through preclinical and early clinical development. The intern will work closely with BA scientists to develop LC–MS assays for clinical biomarkers impacting CYP and transporter drug–drug interaction (DDI) evaluations. Drug metabolizing enzymes and transporters can govern the ADME properties of drugs. The availability of endogenous biomarkers to monitor CYP- and transporter-mediated DDIs in early phases of clinical investigations would greatly benefit downstream clinical studies. A fully validated endogenous biomarker may ultimately replace the need for dedicated clinical DDI studies.

Minimum Qualifications

• Candidate must be enrolled in an undergraduate or graduate degree program in one of the following areas:

o Pharmaceutical sciences, analytical chemistry, biology, and biochemistry.

• Prior experience working with biological samples such as plasma and cells is desirable.

• Hands on experience with analytical instrumentations such as HPLC and mass spectrometry is desirable.

• Basic knowledge of the science of drug metabolism and pharmacokinetics (Absorption, Distribution, Metabolism and Excretion).

Preferred Qualifications

• Ability to integrate, analyze and interpret complex results.

• Excellent written and oral communication skills.

• Detail oriented with the ability to manage multiple priorities while meeting expected deadlines.