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FDA Postdoctoral Research Opportunity in Genome Engineering

*Applications will be reviewed on a rolling-basis.

A research opportunity is currently available in the Office of Tissues and Advanced Therapies (OTAT), at the Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA) in Silver Spring, Maryland.

The goal of this project is to perform research and receive training on cell engineering with an emphasis on genome editing in human stem cells. Under the guidance of a mentor, the participant will be involved in research projects aimed to evaluate safety and efficacy of novel genome editing technologies for gene therapy, as well as to develop new therapeutic approaches. By precise genome editing, the projects also aim to understand cellular and molecular mechanisms in development and diseases, such as in the immune and hematopoietic systems.

The participant will receive mentoring on project design and execution, as well as training in specific techniques used in genome editing, stem cell maintenance and differentiation. Opportunities will also be provided to the participant to present and discuss research projects within the agency and in national research conferences.

Anticipated Appointment Start Date: May 1, 2020

Qualifications
The qualified candidate should have received a bachelor's, master's or doctoral degree in one of the relevant fields, or be currently pursuing one of the degrees and will reach completion by May 1, 2020. Degree must have been received within five years of the appointment start date.

Preferred skills:
  • Demonstrated record or potential of scientific productivity
  • Training in molecular biology, immunology or virology
  • Research experience and proficiency in at least two of the following:molecular cloning
  • flow cytometry
  • cell culture
  • viral vector-mediated gene delivery
  • cellular assays (viability, proliferation, genotoxicity)
  • exosome
  • NGS analysis
  • small animal handling

This opportunity is available to US citizens and Lawful Permanent Residents (LPR) only.

If you have questions, send an email to ORISE.FDA.CBER@orau.org. Please include the reference code for this opportunity (FDA-CBER-2020-0018) in your email.