FDA Sunscreen Safety Fellowship
*Applications will be reviewed on a rolling-basis.
A research opportunity is available in the Office of New Drugs, Center for Drug Evaluation and Research (CDER), Food and Drug Administration (FDA) in Silver Spring, Maryland.
Sunscreen products contain UV-filters as active ingredients for the protection of skin against UV radiation. Dermal absorption data reveals systemic exposure of UV-filters in humans, which can be obtained from clinical maximal usage trials (MUsT). FDA guidance recommends conducting in vitro skin permeation test (IVPT) to help select formulations for the clinical MUsT, as IVPT results may be indicative of in vivo absorption. We aim to develop sensitive and robust IVPT methods which is not available in the literature. In addition, different skin membranes will be used and the most appropriate model will be selected and validated.
Under the guidance of a mentor, the participant will learn to develop and validate methodologies for safety and quality evaluation of sunscreen products. Correlations between the in vitro and in vivo performance of the sunscreen products will be investigated with the help of modeling and prediction software.
Qualifications
The qualified candidate should be currently pursuing or have received a master's or doctoral degree in one of the relevant fields. Degree must have been received within five years of the appointment start date.
If you have questions, send an email to ORISE.FDA.CDER@orau.org. Please include the reference code for this opportunity (FDA-CDER-2020-0525) in your email.