Scientist, Structure-based Protein Engineering
We are seeking a Ph.D. scientist with strong background in structural biology to join the Bispecific Antibodies group. The successful candidate will support our ongoing efforts to design, engineer and characterize next-generation protein-based immune modulators across multiple therapeutic areas including inflammation, oncology, infectious disease and metabolism.
As a Scientist, a typical day may include the following:
• Design and engineer novel immunomodulatory proteins using structural biology and related computational tools
• Perform in vitro and ex vivo assays to characterize therapeutic molecules using engineered cell lines and/or primary human and murine cells
• Collaborate closely with in vivo colleagues to conduct preclinical efficacy studies
• Maintain complete, accurate, and timely record of experiments and data analysis
• Develop in-depth scientific knowledge in relevant therapeutic focus areas, contribute novel ideas to project discussion and decision making
• Present data at group and inter-departmental meetings
• Author documents for regulatory filings, patent applications, and scientific journal publications
• Potentially manage Research Associates as needed
This role may be for you if:
• You have excellent communication, documentation and problem solving skills
• You are enthusiastic about science, looking to expand your knowledge and skillset in cancer immunotherapy
• You are keen on working in a cutting-edge environment to develop novel therapeutics
• You thrive in a creative, flexible, fast-paced collaborative team environment
To be considered for this position, you must have a PhD in structural biology, biochemistry, biophysics or related fields with a strong track record of publication in protein structure studies. Expertise in construct design, expression, purification and characterization is required. Experience in biochemical, cellular, and molecular techniques: cloning, CRISPR gene editing, immunoblotting. Experience in cell culture and in vitro/ex vivo cell-based assays. Additionally, Familiarity with multi-color flow cytometry is a plus.
Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.